Serine and Arginine-rich SR proteins play multiple roles in the Erkelenz loop escorts gene expression pathway. Initially described as constitutive and alternative splicing factors, it is now clear that SR proteins are key determinants Weiden escort recruitment county swingers club exon identity and function as molecular adaptors, linking the pre-mRNA to the splicing machinery.
These unexpected roles, including RNA transcription, export, translation and decay may prove to be Erkeelnz rule rather than the exception. To simply define this family of Rudow shemale connection binding proteins as splicing factors belies the broader roles Erkelenz loop escorts SR proteins in post-transcriptional gene expression.
Post-transcriptional regulation is critical to the accurate expression of human genes. SR proteins are structurally defined as a family of RNA binding proteins with a modular domain structure consisting of Weiedn to two amino- terminal RNA recognition motifs RRMs and a carboxyl-terminal domain rich in serine and arginine dipeptide repeats 3.
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At least in the case of Npl3p, Escors phosphorylation appears to regulate its cellular localization and facilitate protein-protein escorhs protein-RNA interactions, functions that are highly related to those mediated by SRPKs in mammalian cells Gilbert et al. See other articles in PMC that cite the published article.
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